Vial compatibility with solvents

Septa selection guide

• Solvents—some solvents that are commonly used for GC and LC experiments can impact the septa integrity. Use our Chemical Resistance and Septa Solvent Compatibility Sections for more details Contents Choosing the right septa chart 2 Septa selection guide Septa material: General Chromatography vials 3 Septa material: 20 mm headspace septa 4

Extractable and Leachable Challenges

Nov 8, 2017 · solvents (not just water) • pH adjusted water at pH 2.0 and pH 10.0 • Alcohol (50:50 ethanol / water mixture) • Additional organic solvent as determined by drug product vehicle ₋ A new one-time baseline extractable study should be performed on every new ink

Tips and Tricks for HPLC and UHPLC - Thermo Fisher Scientific

• Solvent compatibility • Try to use pre-mixed solvents • Add 5-10% of organic eluent to the aqueous eluent • Add 5-10% aqueous eluent to the organic eluent • Avoids local crystallization in the pump (with buffers) • Eluents with salt buffers • Change eluents with salt buffers regularly • Filtrate buffers

Controlling Contamination in UltraPerformance LC /MS and HPLC

d. Use the smallest solvent reservoir appropriate for your analysis (it will depend on your flow rate and the length of your runs). e. Do not top off solvents. Instead, discard old solvent, rinse the bottles and solvent inlet filters with the solvent that will be used, and then refill with fresh solvent. Finally, do a wet prime.

Septa Selection Tool | Thermo Fisher Scientific - US

The septum you choose for your autosampler vial can impact sample evaporation, sample security, needle bending and blockages, and instrument down time. Don’t let the complexities of septa selection slow you down. Use the simple online Thermo Scientific SureSTART Selection Guide to find the right septa and vial for your analysis.

Teflon PTFE Chemical Compatibility Reference Chart

PTFE Chemical Compatibility Chart: Polytetrafluoroethylene is very non-reactive and ideal for use with most chemicals. Review the chemical compatibility of Teflon® and PTFE with various chemicals, solvents, alcohols and other products in the cart below. Shop PTFE. Please Note: The information in this chart has been supplied by reputable

solvent compatibility ptfe membrane Sigma Aldrich-Analytical

Jan 20, 2022 · Solvent-Resistant Stirred Cells. The Millipore ® Solvent Resistant Stirred Cell is constructed from stainless steel and borosilicate glass for applications requiring compatibility with solvents. It is designed to offer a rapid and efficient method for concentrating or desalting samples of up to 300 mL under high pressure.

Qualification of Headspace High Performance Septa by

20 mL headspace crimp top vials or screw top vials directly; no effort was made to purge the vials with an inert gas prior to capping. These vial blank samples were used for blank background and potential septa contamination evaluation. Solvent blank samples were prepared by adding 1 mL of solvent blank into a vial and then capping the vial

Packaging Selection Guide for Vials, Columns, & Bottles

Glen Research offers a range of vials, columns, and bottles to meet specifications for your applications. µmole. Choose from our selection of vials, columns, and bottles by pack size to meet your lab’s needs. TWIST is a trademark of Glen Research.

Annex 9 Guidelines on packaging for pharmaceutical products

ents and solvents used in a variety of dosage forms. The quality of the packaging of pharmaceutical products plays a very important role in the quality of such products. It must: — protect against all adverse external influences that can alter the properties of the product, e.g. moisture, light, oxygen and tem-perature variations;

Solvent Choice for GC Injection - Crawford Scientific

Polar samples (analytes) generally need a more polar solvent (methanol for example) and less polar analytes a less polar solvent (n-hexane or heptane for example). Sometimes we might even use an intermediate polarity solvent when we aren’t sure of the analyte composition, ethyl acetate is a popular choice in this instance.

Simplifying GC Syringes and Sample Introduction - Aijiren

Washes and Pumps: Solvents Contaminated wash vial bottom Contaminated wash solvent Frequently clean or replace wash vials • Traces of previous samples will accumulate over time • Do not refill or “top-off” the vial, instead empty, rinse, and replace solvent • Use a cotton swab to remove particulates from the glass surface DE.4721759259

TriPlus™ RSH SMART Autosampler - Thermo Fisher Scientific

TriPlus RSH SMART configured for liquid and headspace injections on regular X-axis length. Only for manual tool change. Complete with liquid syringe tool, headspace syringe tool, incubation oven, 2 x 10 µL SMART syringes, 2 x 2.5 mL GT SMART syringes, a standard washing station, 2 tray holders, 3 trays for 2 mL vials, one tray for 10/20 mL vials.

HIGHLIGHTS OF PRESCRIBING INFORMATION DOSAGE FORMS AND

0.9% sodium chloride prior to use. Dilute the contents of one vial of GIAPREZA in 0.9% saline to achieve a final concentration of 5,000 ng/mL or 10,000 ng/mL. Discard vial and any unused portion of the drug product after use. Table 1: Preparation of Diluted Solution . Fluid Restricted?

Exploring the Role of Anti-solvent Effects during Washing on

Apr 4, 2021 · However, sourcing such vials with membrane basket compatible with the solvents used in this study proved difficult. Furthermore, using centrifuge vials which would be more solvent-/air-tight would have allowed for mimicking of the glass vial method, where the solvent system could be allowed to equilibrate over 24 h.