2021年12月16日 · 12月16日， Nature 在线发表了中国科学院分子植物科学卓越创新中心研究员何祖华研究组题为 NLRs guard metabolism to coordinate pattern- and effector-triggered immunity 的研究论文，揭示出一条新的广谱免疫代谢调控网络。 研究发现，水稻广谱抗病NLR受体蛋白通过保护免疫代谢通路免受病原菌攻击，协同整合植物PTI和ETI，进而赋予水稻广谱抗病性的新机
2011年3月1日 · The intracellular protein kinase that it encodes activates an immune response in tomato ( Solanum lycopersicum) to bacterial speck disease by interacting with either the AvrPto or AvrPtoB type III effector proteins that are delivered into the plant cell by Pseudomonas syringae pathovar tomato.
2021年5月18日 · （1）植物通过细胞膜定位的模式识别受体（PRRs）直接识别病原菌的病原相关分子模式（PAMPs）而触发植物的第一层免疫系统（pattern-triggered immunity, PTI），来抵抗病原菌的侵染。 （2）成功入侵的病原菌会向植物细胞内分泌毒性蛋白，进而攻击植物的免疫系统以便其进一步侵染植物，植物会通过细胞内的NLR受体蛋白直接或间接地识别病原菌的效应
2011年6月13日 · Another branch of innate immune signaling is activated when individual pathogen effectors are recognized by disease resistance (R) proteins, resulting in effector-triggered immunity (ETI). In addition, the plant immune responses are regulated by several plant hormones, including salicylic acid (SA), jasmonic acid (JA), and ethylene ( 4, 5 ).
2022年9月29日 · In the last decade, a major dogma in the field of immunology has been called into question by the identification of a cell autonomous innate immune memory. This innate immune memory (also named trained immunity) was found to be mostly carried by innate immune cells and to be characterized by an exacerbated inflammatory response with a
2017年5月30日 · Genetic control of plant diseases has traditionally included the deployment of single immune receptors with nucleotide-binding leucine-rich repeat (NLR) domain architecture. These NLRs recognize corresponding pathogen effector proteins inside plant cells, resulting in effector-triggered immunity (ETI). Although ETI triggers robust resistance, deployment of
Effector-triggered immunity - Wikipedia Effector-triggered immunity The host cell detects the presence of the pathogen directly from the molecular patterns on the pathogen and indirectly
Pseudomonas 属や Xanthomonas 属の病原細菌は針状の構造をしたIII型分泌装置を用いて宿主の細胞内にエフェクターを分泌している．III型分泌装置を構成するタンパク質をコードする遺伝子は hrp （hypersensitive response and pathogenicity）遺伝子とよばれ，この hrp 遺伝子は植物へ感染するときのみ発現する．つまり，病原細菌は宿主の組織内の環境を感知してIII型分泌装
2019年12月19日 · Several mechanisms of effector-triggered immune responses have been proposed in plants, including two well-studied models. a, In the ‘gene-for-gene’ model, a
2014年5月6日 · Effectors are directly capable of triggering an immune response through transcriptional regulation. Effectors can also disrupt cellular processes such as protein translation and cytoskeletal remodeling, which will trigger an immune response. Some bacterial effectors activate Rho-GTPases, which facilitate bacterial entry and can also trigger ETI.
2021年12月16日 · 植物的免疫系统分为Pattern-triggered immunity (PTI) 和efector-triggered immunity (ETI)两个部分，用以感知体外的病原物入侵。 蛋氨酸（Methionine ，Met）是乙烯的合成前体。 病原菌经常挟持乙烯以促进自己定殖。 虽然初级代谢物已经被认定参与了植物的防御，但它们的免疫功能以及NLR蛋白激活其生物合成的机制尚不清楚。 稻瘟菌（Magnaporthe
We carried out screens aimed at identifying the determinant (s) suppressing HopZ1a-triggered and HopZ3-triggered immunity within their native strains, and identified several effectors
2022年5月11日 · However, mechanisms underlying effector-triggered inhibition of nodulation remain largely unknown. Nodulation outer protein T (NopT) of Sinorhizobium sp. NGR234 is an effector protease related to the Pseudomonas effector Avirulence protein Pseudomonas phaseolicola B (AvrPphB).
2010年6月30日 · Some of the effector proteins were initially identified as products of avirulence (Avr) genes conditioning resistance (R) protein-mediated defences, termed effector-triggered innate immunity (ETI), in plants (Boller and He, 2009; ;
